Guo Huang, PhD

Associate Prof in Residence
Cardiovascular Research Inst
+1 415 502-2873

B.S. Peking University (summa cum laude)
Ph.D. Johns Hopkins Medical Institute (Phi Beta Kappa)
Postdoc. UT Southwestern Medical Center (Life Sciences Research Foundation Fellow)


Adrenergic-Thyroid Hormone Interactions Drive Postnatal Thermogenesis and Loss of Mammalian Heart Regenerative Capacity.


Payumo AY, Chen X, Hirose K, Chen X, Hoang A, Khyeam S, Yu H, Wang J, Chen Q, Powers N, Chen L, Bigley RB, Lovas J, Hu G, Huang GN

Vertebrate cardiac regeneration: evolutionary and developmental perspectives.

Cell regeneration (London, England)

Cutie S, Huang GN

Hormonal control of cardiac regenerative potential.

Endocrine connections

Amram AV, Cutie S, Huang GN

KrasP34R and KrasT58I mutations induce distinct RASopathy phenotypes in mice.

JCI insight

Wong JC, Perez-Mancera PA, Huang TQ, Kim J, Grego-Bessa J, Del Pilar Alzamora M, Kogan SC, Sharir A, Keefe SH, Morales CE, Schanze D, Castel P, Hirose K, Huang GN, Zenker M, Sheppard D, Klein OD, Tuveson DA, Braun BS, Shannon K

The coevolutionary process of restaurant CSR in the time of mega disruption.

International journal of hospitality management

Ou J, Wong IA, Huang GI

Lamin B2, Guardian of Cardiomyocyte Nuclear Division.

Developmental cell

Payumo AY, Huang GN

Evidence for hormonal control of heart regenerative capacity during endothermy acquisition.

Science (New York, N.Y.)

Hirose K, Payumo AY, Cutie S, Hoang A, Zhang H, Guyot R, Lunn D, Bigley RB, Yu H, Wang J, Smith M, Gillett E, Muroy SE, Schmid T, Wilson E, Field KA, Reeder DM, Maden M, Yartsev MM, Wolfgang MJ, Grützner F, Scanlan TS, Szweda LI, Buffenstein R, Hu G, Flamant F, Olgin JE, Huang GN

Unconventional Functions of Muscles in Planarian Regeneration.

Developmental cell

Cutie S, Hoang AT, Payumo AY, Huang GN

Insights into nuclear dynamics using live-cell imaging approaches.

Wiley interdisciplinary reviews. Systems biology and medicine

Bigley RB, Payumo AY, Alexander JM, Huang GN

Isolation, Culture and Transduction of Adult Mouse Cardiomyocytes.

Journal of visualized experiments : JoVE

Judd J, Lovas J, Huang GN

C/EBP transcription factors mediate epicardial activation during heart development and injury.

Science (New York, N.Y.)

Huang GN, Thatcher JE, McAnally J, Kong Y, Qi X, Tan W, DiMaio JM, Amatruda JF, Gerard RD, Hill JA, Bassel-Duby R, Olson EN

Heart repair by reprogramming non-myocytes with cardiac transcription factors.


Song K, Nam YJ, Luo X, Qi X, Tan W, Huang GN, Acharya A, Smith CL, Tallquist MD, Neilson EG, Hill JA, Bassel-Duby R, Olson EN

Peptidyl-prolyl isomerase FKBP52 controls chemotropic guidance of neuronal growth cones via regulation of TRPC1 channel opening.


Shim S, Yuan JP, Kim JY, Zeng W, Huang G, Milshteyn A, Kern D, Muallem S, Ming GL, Worley PF

STIM1 gates TRPC channels, but not Orai1, by electrostatic interaction.

Molecular cell

Zeng W, Yuan JP, Kim MS, Choi YJ, Huang GN, Worley PF, Muallem S

NFAT binding and regulation of T cell activation by the cytoplasmic scaffolding Homer proteins.

Science (New York, N.Y.)

Huang GN, Huso DL, Bouyain S, Tu J, McCorkell KA, May MJ, Zhu Y, Lutz M, Collins S, Dehoff M, Kang S, Whartenby K, Powell J, Leahy D, Worley PF

STIM1 heteromultimerizes TRPC channels to determine their function as store-operated channels.

Nature cell biology

Yuan JP, Zeng W, Huang GN, Worley PF, Muallem S

STIM1 carboxyl-terminus activates native SOC, I(crac) and TRPC1 channels.

Nature cell biology

Huang GN, Zeng W, Kim JY, Yuan JP, Han L, Muallem S, Worley PF

Research Area: 
Adipocyte and Metabolism