Jean-Marc Schwarz, PhD | Nutrition Obesity Research Center

Effect of weight gain on blood pressure in Ugandan persons with HIV on dolutegravir/lamivudine/ tenofovir disoproxil fumarate over 48 weeks.

PloS one

Amutuhaire W, Castelnuovo B, Brusselaers N, Nabwana M, Muhammad L, Maloney B, Nixon B, Schwarz JM, Mulindwa F

Leukocyte telomere length change in children with obesity in the context of an isocaloric fructose restriction intervention.

Diabetology & metabolic syndrome

Wojcicki JM, Epel E, Lin J, Tai V, Schwarz JM, Noworolski SM, Erkin-Cakmak A, Mulligan K, Gugliucci A, Lustig RH

Blood glucose outcomes of anti-retroviral therapy naïve Ugandan people with HIV with pre-diabetes mellitus initiated on dolutegravir for 48 weeks.

BMC infectious diseases

Mulindwa F, Schwarz JM, Brusselaers N, Nabwana M, Bollinger R, Buzibye A, Amutuhaire W, Yendewa G, Odongpiny ELA, Kiguba R, Castelnuovo B

Effects of Consuming Beverages Sweetened with Fructose, Glucose, High-Fructose Corn Syrup, Sucrose, or Aspartame on OGTT-Derived Indices of Insulin Sensitivity in Young Adults.

Nutrients

Hieronimus B, Medici V, Lee V, Nunez MV, Sigala DM, Bremer AA, Cox CL, Keim NL, Schwarz JM, Pacini G, Tura A, Havel PJ, Stanhope KL

Should dolutegravir always be withheld in people with HIV on dolutegravir with incident diabetes mellitus? a case report.

BMC infectious diseases

Mulindwa F, Castelnuovo B, Brusselaers N, Bollinger R, Yendewa G, Amutuhaire W, Mukashaka C, Schwarz JM

Dolutegravir use over 48 weeks is not associated with worsening insulin resistance and pancreatic beta cell function in a cohort of HIV-infected Ugandan adults.

AIDS research and therapy

Mulindwa F, Castelnuovo B, Brusselaers N, Nabwana M, Bollinger R, Buzibye A, Agnes Odongpiny EL, Kiguba R, Schwarz JM

Dolutegravir use over 48 weeks is not associated with worsening insulin resistance and pancreatic beta cell function in a cohort of HIV-infected Ugandan adults.

Research square

Mulindwa F, Castelnuovo B, Brusselaers N, Nabwana M, Bollinger R, Laker E, Kiguba R, Schwarz JM

Prevalence of Cardiometabolic Disease Risk Factors in People With HIV Initiating Antiretroviral Therapy at a High-Volume HIV Clinic in Kampala, Uganda.

Open forum infectious diseases

Amutuhaire W, Mulindwa F, Castelnuovo B, Brusselaers N, Schwarz JM, Edrisa M, Dujanga S, Salata RA, Yendewa GA

Implementation of longitudinal insulin kinetic studies in busy field settings in Uganda: experience from the "glucose metabolism changes in Ugandan HIV patients on dolutegravir based anti-retroviral therapy" (GLUMED study).

The Pan African medical journal

Mulindwa F, Schwarz JM, Brusselaers N, Dujanga S, Yendewa G, Castelnuovo B

Blood glucose trajectories and incidence of diabetes mellitus in Ugandan people living with HIV initiated on dolutegravir.

AIDS research and therapy

Mulindwa F, Castelnuovo B, Brusselaers N, Bollinger R, Rhein J, Edrisa M, Buzibye A, Amutuhaire W, Yendewa G, Nabaggala S, Odongpiny ELA, Kiguba R, Nakawooza A, Dujanga S, Nabwana M, Schwarz JM

Association between integrase strand transfer inhibitor use with insulin resistance and incident diabetes mellitus in persons living with HIV: a systematic review and meta-analysis.

BMJ open diabetes research & care

Mulindwa F, Kamal H, Castelnuovo B, Byonanebye DM, Schwarz JM, Bollinger R, Brusselaers N

Effects of Isocaloric Fructose Restriction on Ceramide Levels in Children with Obesity and Cardiometabolic Risk: Relation to Hepatic De Novo Lipogenesis and Insulin Sensitivity.

Nutrients

Olson E, Suh JH, Schwarz JM, Noworolski SM, Jones GM, Barber JR, Erkin-Cakmak A, Mulligan K, Lustig RH, Mietus-Snyder M

Association between integrase strand transfer inhibitor (INSTIs) use with insulin resistance and incident diabetes mellitus in persons living with HIV: A systematic review and meta-analysis protocol.

PloS one

Mulindwa F, Kamal H, Castelnuovo B, Bollinger RC, Schwarz JM, Brussealers N

Separation of postprandial lipoproteins: improved purification of chylomicrons using an ApoB100 immunoaffinity method.

Journal of lipid research

Jones GM, Caccavello R, Palii SP, Pullinger CR, Kane JP, Mulligan K, Gugliucci A, Schwarz JM

Isocaloric Fructose Restriction Reduces Serum d-Lactate Concentration in Children With Obesity and Metabolic Syndrome.

The Journal of clinical endocrinology and metabolism

Erkin-Cakmak A, Bains Y, Caccavello R, Noworolski SM, Schwarz JM, Mulligan K, Lustig RH, Gugliucci A

An ethanolic extract of Artemisia scoparia inhibits lipolysis in vivo and has antilipolytic effects on murine adipocytes in vitro.

American journal of physiology. Endocrinology and metabolism

Boudreau A, Richard AJ, Burrell JA, King WT, Dunn R, Schwarz JM, Ribnicky DM, Rood J, Salbaum JM, Stephens JM

Dietary carbohydrates and fatty liver disease: de novo lipogenesis.

Current opinion in clinical nutrition and metabolic care

Chiu S, Mulligan K, Schwarz JM

Conversion of Sugar to Fat: Is Hepatic de Novo Lipogenesis Leading to Metabolic Syndrome and Associated Chronic Diseases?

The Journal of the American Osteopathic Association

Schwarz JM, Clearfield M, Mulligan K

Effects of Dietary Fructose Restriction on Liver Fat, De Novo Lipogenesis, and Insulin Kinetics in Children With Obesity.

Gastroenterology

Schwarz JM, Noworolski SM, Erkin-Cakmak A, Korn NJ, Wen MJ, Tai VW, Jones GM, Palii SP, Velasco-Alin M, Pan K, Patterson BW, Gugliucci A, Lustig RH, Mulligan K

Short-term isocaloric fructose restriction lowers apoC-III levels and yields less atherogenic lipoprotein profiles in children with obesity and metabolic syndrome.

Atherosclerosis

Gugliucci A, Lustig RH, Caccavello R, Erkin-Cakmak A, Noworolski SM, Tai VW, Wen MJ, Mulligan K, Schwarz JM

In vivo triglyceride synthesis in subcutaneous adipose tissue of humans correlates with plasma HDL parameters.

Atherosclerosis

Tuvdendorj D, Munoz AO, Ruiz-Barros V, Schwarz JM, Montalto G, Chandalia M, Sowers LC, Rizzo M, Murphy EJ, Abate N

Isocaloric fructose restriction and metabolic improvement in children with obesity and metabolic syndrome.

Obesity (Silver Spring, Md.)

Lustig RH, Mulligan K, Noworolski SM, Tai VW, Wen MJ, Erkin-Cakmak A, Gugliucci A, Schwarz JM

Effect of a High-Fructose Weight-Maintaining Diet on Lipogenesis and Liver Fat.

The Journal of clinical endocrinology and metabolism

Schwarz JM, Noworolski SM, Wen MJ, Dyachenko A, Prior JL, Weinberg ME, Herraiz LA, Tai VW, Bergeron N, Bersot TP, Rao MN, Schambelan M, Mulligan K

Subchronic sleep restriction causes tissue-specific insulin resistance.

The Journal of clinical endocrinology and metabolism

Rao MN, Neylan TC, Grunfeld C, Mulligan K, Schambelan M, Schwarz JM

Effects of the absence of apolipoprotein e on lipoproteins, neurocognitive function, and retinal function.

JAMA neurology

Mak AC, Pullinger CR, Tang LF, Wong JS, Deo RC, Schwarz JM, Gugliucci A, Movsesyan I, Ishida BY, Chu C, Poon A, Kim P, Stock EO, Schaefer EJ, Asztalos BF, Castellano JM, Wyss-Coray T, Duncan JL, Miller BL, Kane JP, Kwok PY, Malloy MJ

Thermogenic changes after gastric bypass, adjustable gastric banding or diet alone.

Surgery

Rabl C, Rao MN, Schwarz JM, Mulligan K, Campos GM

Effect of 8 weeks of overfeeding on ectopic fat deposition and insulin sensitivity: testing the "adipose tissue expandability" hypothesis.

Diabetes care

Johannsen DL, Tchoukalova Y, Tam CS, Covington JD, Xie W, Schwarz JM, Bajpeyi S, Ravussin E

Response to comment on Lecoultre et al. Ten nights of moderate hypoxia improves insulin sensitivity in obese humans. Diabetes care 2013;36:e197-e198.

Diabetes care

Peterson CM, Lecoultre V, Schwarz JM, Ravussin E

Effects of Artemisia species on de novo lipogenesis in vivo.

Nutrition (Burbank, Los Angeles County, Calif.)

Rood JC, Schwarz JM, Gettys T, Mynatt RL, Mendoza T, Johnson WD, Cefalu WT

Ten nights of moderate hypoxia improves insulin sensitivity in obese humans.

Diabetes care

Lecoultre V, Peterson CM, Covington JD, Ebenezer PJ, Frost EA, Schwarz JM, Ravussin E

Changes in post-prandial glucose and pancreatic hormones, and steady-state insulin and free fatty acids after gastric bypass surgery.

Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery

Campos GM, Rabl C, Havel PJ, Rao M, Schwarz JM, Schambelan M, Mulligan K

Adverse metabolic effects of dietary fructose: results from the recent epidemiological, clinical, and mechanistic studies.

Current opinion in lipidology

Stanhope KL, Schwarz JM, Havel PJ

Consumption of fructose- but not glucose-sweetened beverages for 10 weeks increases circulating concentrations of uric acid, retinol binding protein-4, and gamma-glutamyl transferase activity in overweight/obese humans.

Nutrition & metabolism

Cox CL, Stanhope KL, Schwarz JM, Graham JL, Hatcher B, Griffen SC, Bremer AA, Berglund L, McGahan JP, Keim NL, Havel PJ

Circulating concentrations of monocyte chemoattractant protein-1, plasminogen activator inhibitor-1, and soluble leukocyte adhesion molecule-1 in overweight/obese men and women consuming fructose- or glucose-sweetened beverages for 10 weeks.

The Journal of clinical endocrinology and metabolism

Cox CL, Stanhope KL, Schwarz JM, Graham JL, Hatcher B, Griffen SC, Bremer AA, Berglund L, McGahan JP, Keim NL, Havel PJ

Metabolic responses to prolonged consumption of glucose- and fructose-sweetened beverages are not associated with postprandial or 24-h glucose and insulin excursions.

The American journal of clinical nutrition

Stanhope KL, Griffen SC, Bremer AA, Vink RG, Schaefer EJ, Nakajima K, Schwarz JM, Beysen C, Berglund L, Keim NL, Havel PJ

Boosting dose ritonavir does not alter peripheral insulin sensitivity in healthy HIV-seronegative volunteers.

Journal of acquired immune deficiency syndromes (1999)

Taylor SA, Lee GA, Pao VY, Anthonypillai J, Aweeka FT, Schwarz JM, Mulligan K, Schambelan M, Grunfeld C

Effects of insulin-like growth factor (IGF)-I/IGF-binding protein-3 treatment on glucose metabolism and fat distribution in human immunodeficiency virus-infected patients with abdominal obesity and insulin resistance.

The Journal of clinical endocrinology and metabolism

Rao MN, Mulligan K, Tai V, Wen MJ, Dyachenko A, Weinberg M, Li X, Lang T, Grunfeld C, Schwarz JM, Schambelan M

Reduced oxygenation in human obese adipose tissue is associated with impaired insulin suppression of lipolysis.

The Journal of clinical endocrinology and metabolism

Pasarica M, Rood J, Ravussin E, Schwarz JM, Smith SR, Redman LM

The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome.

Nature reviews. Gastroenterology & hepatology

Lim JS, Mietus-Snyder M, Valente A, Schwarz JM, Lustig RH

The protease inhibitor combination lopinavir/ritonavir does not decrease insulin secretion in healthy, HIV-seronegative volunteers.

AIDS (London, England)

Pao VY, Lee GA, Taylor S, Aweeka FT, Schwarz JM, Mulligan K, Schambelan M, Grunfeld C

Improvement in peripheral glucose uptake after gastric bypass surgery is observed only after substantial weight loss has occurred and correlates with the magnitude of weight lost.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract

Campos GM, Rabl C, Peeva S, Ciovica R, Rao M, Schwarz JM, Havel P, Schambelan M, Mulligan K

The acute effects of HIV protease inhibitors on insulin suppression of glucose production in healthy HIV-negative men.

Journal of acquired immune deficiency syndromes (1999)

Lee GA, Schwarz JM, Patzek S, Kim S, Dyachenko A, Wen M, Mulligan K, Schambelan M, Grunfeld C

Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans.

The Journal of clinical investigation

Stanhope KL, Schwarz JM, Keim NL, Griffen SC, Bremer AA, Graham JL, Hatcher B, Cox CL, Dyachenko A, Zhang W, McGahan JP, Seibert A, Krauss RM, Chiu S, Schaefer EJ, Ai M, Otokozawa S, Nakajima K, Nakano T, Beysen C, Hellerstein MK, Berglund L, Havel PJ