
Asst Professor
M_Physiology
Research Area
+1 415 476-2308
Publications
ADPKD-Causing Missense Variants in Polycystin-1 Disrupt Cell Surface Localization or Polycystin Channel Function.
bioRxiv : the preprint server for biology
Cilia-enriched oxysterol 7β,27-DHC is required for polycystin ion channel activation.
Nature communications
The Concise Guide to PHARMACOLOGY 2023/24: Ion channels.
British journal of pharmacology
Conversion of anterograde into retrograde trains is an intrinsic property of intraflagellar transport.
Current biology : CB
Electrophysiological Recordings of the Polycystin Complex in the Primary Cilium of Cultured Mouse IMCD-3 Cell Line.
Bio-protocol
THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Ion channels.
British journal of pharmacology
New insights into ion channel-dependent signalling during left-right patterning.
The Journal of physiology
MCOLN1 is a ROS sensor in lysosomes that regulates autophagy.
Nature communications
Direct Recording and Molecular Identification of the Calcium Channel of Primary Cilia.
Biophysical Journal
Molecular dynamics of ion transport through the open conformation of a bacterial voltage-gated sodium channel.
Proceedings of the National Academy of Sciences of the United States of America
Cleavage of TRPM7 releases the kinase domain from the ion channel and regulates its participation in Fas-induced apoptosis.
Developmental cell
Transient receptor potential cation channel, subfamily C, member 5 (TRPC5) is a cold-transducer in the peripheral nervous system.
Proceedings of the National Academy of Sciences of the United States of America
PI(3,5)P2 Controls Membrane Trafficking by Direct Activation of Mucolipin Ca2+ Release Channels in the Endolysosome.
Biophysical Journal
PI(3,5)P(2) controls membrane trafficking by direct activation of mucolipin Ca(2+) release channels in the endolysosome.
Nature communications
Activating mutations of the TRPML1 channel revealed by proline-scanning mutagenesis.
The Journal of biological chemistry
Activation Mutations of the TRPML1 Channel Revealed by Proline Scanning Mutagenesis.
Biophysical Journal
The Type IV Mucolipidosis-Associated Protein TRPML1 is an Endolysosomal Iron Release Channel.
Biophysical Journal
The type IV mucolipidosis-associated protein TRPML1 is an endolysosomal iron release channel.
Nature
Fibroblast growth factor-regulated palmitoylation of the neural cell adhesion molecule determines neuronal morphogenesis.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Activating mutation in a mucolipin transient receptor potential channel leads to melanocyte loss in varitint-waddler mice.
Proceedings of the National Academy of Sciences of the United States of America
Oregano, thyme and clove-derived flavors and skin sensitizers activate specific TRP channels.
Nature neuroscience
An introduction to TRP channels.
Annual review of physiology
The Role of Lipid Rafts in Signal Transduction and Synaptic Plasticity of Neural Cells.
Membrane Microdomain Signaling
Polysialylated neural cell adhesion molecule promotes remodeling and formation of hippocampal synapses.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Rapid and efficient electroporation-based gene transfer into primary dissociated neurons.
Journal of neuroscience methods
Neural cell adhesion molecule promotes accumulation of TGN organelles at sites of neuron-to-neuron contacts.
The Journal of cell biology
The neural cell adhesion molecule regulates cell-surface delivery of G-protein-activated inwardly rectifying potassium channels via lipid rafts.
The Journal of neuroscience : the official journal of the Society for Neuroscience
What can we learn from explanted endovascular devices?
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery
Cosignaling of NCAM via lipid rafts and the FGF receptor is required for neuritogenesis.
The Journal of cell biology
Anxiety and increased 5-HT1A receptor response in NCAM null mutant mice.
Journal of neurobiology