
Professor
M_Physiology
Research Area
+1 415 514-4103
Publications
Dietary restriction promotes neuronal resilience via ADIOL.
bioRxiv : the preprint server for biology
The steroid hormone ADIOL promotes learning by reducing neural kynurenic acid levels.
Genes & development
Identifying lipid particle sub-types in live Caenorhabditis elegans with two-photon fluorescence lifetime imaging.
Frontiers in chemistry
Better living through communal eating.
Cell host & microbe
Neural production of kynurenic acid in Caenorhabditis elegans requires the AAT-1 transporter.
Genes & development
Spectroscopic coherent Raman imaging of Caenorhabditis elegans reveals lipid particle diversity.
Nature chemical biology
Intestinal peroxisomal fatty acid β-oxidation regulates neural serotonin signaling through a feedback mechanism.
PLoS biology
Tau/MAPT disease-associated variant A152T alters tau function and toxicity via impaired retrograde axonal transport.
Human molecular genetics
Kynurenic acid accumulation underlies learning and memory impairment associated with aging.
Genes & development
Phenotypic, chemical and functional characterization of cyclic nucleotide phosphodiesterase 4 (PDE4) as a potential anthelmintic drug target.
PLoS neglected tropical diseases
Investigating Connections between Metabolism, Longevity, and Behavior in Caenorhabditis elegans.
Trends in endocrinology and metabolism: TEM
Conserved Genetic Interactions between Ciliopathy Complexes Cooperatively Support Ciliogenesis and Ciliary Signaling.
PLoS genetics
Neural Regulatory Pathways of Feeding and Fat in Caenorhabditis elegans.
Annual review of genetics
Insights and challenges in using C. elegans for investigation of fat metabolism.
Critical reviews in biochemistry and molecular biology
OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin.
Proceedings of the National Academy of Sciences of the United States of America
Loss of a neural AMP-activated kinase mimics the effects of elevated serotonin on fat, movement, and hormonal secretions.
PLoS genetics
AMP-activated kinase links serotonergic signaling to glutamate release for regulation of feeding behavior in C. elegans.
Cell metabolism
Analyses of C. elegans fat metabolic pathways.
Methods in cell biology
A whole-organism screen identifies new regulators of fat storage.
Nature chemical biology
Regulation of C. elegans fat uptake and storage by acyl-CoA synthase-3 is dependent on NR5A family nuclear hormone receptor nhr-25.
Cell metabolism
mTOR complex-2 activates ENaC by phosphorylating SGK1.
Journal of the American Society of Nephrology : JASN
Caenorhabditis elegans as an emerging model for studying the basic biology of obesity.
Disease models & mechanisms
Rictor/TORC2 regulates Caenorhabditis elegans fat storage, body size, and development through sgk-1.
PLoS biology
Fat rationing in dauer times.
Cell metabolism
C. elegans fat storage and metabolic regulation.
Biochimica et biophysica acta
A TRPV channel modulates C. elegans neurosecretion, larval starvation survival, and adult lifespan.
PLoS genetics
Neural and molecular dissection of a C. elegans sensory circuit that regulates fat and feeding.
Cell metabolism
Serotonin regulates C. elegans fat and feeding through independent molecular mechanisms.
Cell metabolism
Impaired processing of FLP and NLP peptides in carboxypeptidase E (EGL-21)-deficient Caenorhabditis elegans as analyzed by mass spectrometry.
Journal of neurochemistry
Obesity and the regulation of fat metabolism.
WormBook : the online review of C. elegans biology
Mapping out starvation responses.
Cell metabolism