Guo Huang, PhD

Associate Prof in Residence

M_Cardiovascular Research Inst

Research Area

+1 415 502-2873

B.S. Peking University (summa cum laude)
Ph.D. Johns Hopkins Medical Institute (Phi Beta Kappa)
Postdoc. UT Southwestern Medical Center (Life Sciences Research Foundation Fellow)

Publications

Why some hearts heal and others don't: The phylogenetic landscape of cardiac regenerative capacity.

Seminars in cell & developmental biology

Nakamura M, Huang GN

Heart regeneration from the whole-organism perspective to single-cell resolution.

NPJ Regenerative medicine

Chen X, Zhong X, Huang GN

Quantitative label-free digital holographic imaging of cardiomyocyte optical volume, nucleation, and cell division.

Journal of molecular and cellular cardiology

Huang H, Park S, Ross I, Moreno J, Khyeam S, Simmons J, Huang GN, Payumo AY

Ophthalmic acid is a bloodborne metabolite that contributes to age-induced cardiomyocyte hypertrophy.

bioRxiv : the preprint server for biology

Mehdipour M, Park S, Wei W, Long JZ, Huang GN

PD-1-PD-L1 immunomodulatory pathway regulates cardiac regeneration.

Nature cardiovascular research

Qin J, Huang GN, Moslehi J

An injury-responsive mmp14b enhancer is required for heart regeneration.

Science advances

Zlatanova I, Sun F, Wu RS, Chen X, Lau BH, Colombier P, Sinha T, Celona B, Xu SM, Materna SC, Huang GN, Black BL

Quantitative Three-dimensional Label-free Digital Holographic Imaging of Cardiomyocyte Size, Ploidy, and Cell Division.

bioRxiv : the preprint server for biology

Park S, Huang H, Ross I, Moreno J, Khyeam S, Simmons J, Huang GN, Payumo AY

Two decades of heart regeneration research: Cardiomyocyte proliferation and beyond.

WIREs mechanisms of disease

Huang H, Huang GN, Payumo AY

Unlocking cardiomyocyte renewal potential for myocardial regeneration therapy.

Journal of molecular and cellular cardiology

Mehdipour M, Park S, Huang GN

Visualization of regenerating and repairing hearts.

Clinical science (London, England : 1979)

Powers N, Huang GN

Mending a broken heart with novel cardiogenic small molecules.

Cell regeneration (London, England)

Powers N, Huang GN

Adrenergic-Thyroid Hormone Interactions Drive Postnatal Thermogenesis and Loss of Mammalian Heart Regenerative Capacity.

Circulation

Payumo AY, Chen X, Hirose K, Chen X, Hoang A, Khyeam S, Yu H, Wang J, Chen Q, Powers N, Chen L, Bigley RB, Lovas J, Hu G, Huang GN

Endocrine Influence on Cardiac Metabolism in Development and Regeneration.

Endocrinology

Graham N, Huang GN

Genetic, Epigenetic, and Post-Transcriptional Basis of Divergent Tissue Regenerative Capacities Among Vertebrates.

Advanced genetics (Hoboken, N.J.)

Khyeam S, Lee S, Huang GN

Vertebrate cardiac regeneration: evolutionary and developmental perspectives.

Cell regeneration (London, England)

Cutie S, Huang GN

Hormonal control of cardiac regenerative potential.

Endocrine connections

Amram AV, Cutie S, Huang GN

KrasP34R and KrasT58I mutations induce distinct RASopathy phenotypes in mice.

JCI insight

Wong JC, Perez-Mancera PA, Huang TQ, Kim J, Grego-Bessa J, Del Pilar Alzamora M, Kogan SC, Sharir A, Keefe SH, Morales CE, Schanze D, Castel P, Hirose K, Huang GN, Zenker M, Sheppard D, Klein OD, Tuveson DA, Braun BS, Shannon K

The coevolutionary process of restaurant CSR in the time of mega disruption.

International journal of hospitality management

Ou J, Wong IA, Huang GI

In vitro and in vivo roles of glucocorticoid and vitamin D receptors in the control of neonatal cardiomyocyte proliferative potential.

Journal of molecular and cellular cardiology

Cutie S, Payumo AY, Lunn D, Huang GN

Lamin B2, Guardian of Cardiomyocyte Nuclear Division.

Developmental cell

Payumo AY, Huang GN

Defined factors to reactivate cell cycle activity in adult mouse cardiomyocytes.

Scientific reports

Judd J, Lovas J, Huang GN

Evidence for hormonal control of heart regenerative capacity during endothermy acquisition.

Science (New York, N.Y.)

Hirose K, Payumo AY, Cutie S, Hoang A, Zhang H, Guyot R, Lunn D, Bigley RB, Yu H, Wang J, Smith M, Gillett E, Muroy SE, Schmid T, Wilson E, Field KA, Reeder DM, Maden M, Yartsev MM, Wolfgang MJ, Grützner F, Scanlan TS, Szweda LI, Buffenstein R, Hu G, Flamant F, Olgin JE, Huang GN

Peptidyl-prolyl isomerase FKBP52 controls chemotropic guidance of neuronal growth cones via regulation of TRPC1 channel opening.

Neuron

Shim S, Yuan JP, Kim JY, Zeng W, Huang G, Milshteyn A, Kern D, Muallem S, Ming GL, Worley PF

Publications

Why some hearts heal and others don't: The phylogenetic landscape of cardiac regenerative capacity.

Heart regeneration from the whole-organism perspective to single-cell resolution.

Quantitative label-free digital holographic imaging of cardiomyocyte optical volume, nucleation, and cell division.

Ophthalmic acid is a bloodborne metabolite that contributes to age-induced cardiomyocyte hypertrophy.

PD-1-PD-L1 immunomodulatory pathway regulates cardiac regeneration.

An injury-responsive mmp14b enhancer is required for heart regeneration.

Quantitative Three-dimensional Label-free Digital Holographic Imaging of Cardiomyocyte Size, Ploidy, and Cell Division.

Two decades of heart regeneration research: Cardiomyocyte proliferation and beyond.

Unlocking cardiomyocyte renewal potential for myocardial regeneration therapy.

Visualization of regenerating and repairing hearts.

Mending a broken heart with novel cardiogenic small molecules.

Adrenergic-Thyroid Hormone Interactions Drive Postnatal Thermogenesis and Loss of Mammalian Heart Regenerative Capacity.

Endocrine Influence on Cardiac Metabolism in Development and Regeneration.

Genetic, Epigenetic, and Post-Transcriptional Basis of Divergent Tissue Regenerative Capacities Among Vertebrates.

Vertebrate cardiac regeneration: evolutionary and developmental perspectives.

Hormonal control of cardiac regenerative potential.

KrasP34R and KrasT58I mutations induce distinct RASopathy phenotypes in mice.

The coevolutionary process of restaurant CSR in the time of mega disruption.

In vitro and in vivo roles of glucocorticoid and vitamin D receptors in the control of neonatal cardiomyocyte proliferative potential.

Lamin B2, Guardian of Cardiomyocyte Nuclear Division.

Defined factors to reactivate cell cycle activity in adult mouse cardiomyocytes.

Evidence for hormonal control of heart regenerative capacity during endothermy acquisition.

Unconventional Functions of Muscles in Planarian Regeneration.

Insights into nuclear dynamics using live-cell imaging approaches.

Isolation, Culture and Transduction of Adult Mouse Cardiomyocytes.

C/EBP transcription factors mediate epicardial activation during heart development and injury.

Heart repair by reprogramming non-myocytes with cardiac transcription factors.

Biotinylation of Cell Surface Proteins.

T Cell Calcium Mobilization Study (Flow Cytometry).

Peptidyl-prolyl isomerase FKBP52 controls chemotropic guidance of neuronal growth cones via regulation of TRPC1 channel opening.

STIM1 gates TRPC channels, but not Orai1, by electrostatic interaction.

NFAT binding and regulation of T cell activation by the cytoplasmic scaffolding Homer proteins.

STIM1 heteromultimerizes TRPC channels to determine their function as store-operated channels.

STIM1 carboxyl-terminus activates native SOC, I(crac) and TRPC1 channels.