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Mouse Metabolism and Imaging (Core B)

Human Metabolism I Mouse Metabolism and Imaging I Genetics and Genomics


Allison Xu, Director

NORC members wishing to benefit from NORC support accessing these services please contact this Allison Xu: Allison.Xu@ucsf.edu

Services Supported by the NORC Mouse Metabolism and Imaging


Service Area 1: Mouse Metabolism

Provide technical support for UCSF investigators to conduct metabolic studies using a 16-chambered Comprehensive Lab Animal Monitoring System (CLAMS), a Rodent Incubator, an EchoMRI, and Dual energy X-ray absorptiometry, which together allow measurement of food intake, water intake, motor activities, core temperature, and body composition in live mice. The use of these instruments allows longitudinal measurements of key metabolic parameters in the same cohort of animals at different ages and under different feeding conditions, and will enable the accumulation of data over several months of time. We are very excited to offer access to a last generation Seahorse Bioscience XFe24 Extracellular Flux Analyzer, a platform for metabolic assays, simultaneously measuring the two major energy producing pathways of the cell – mitochondrial respiration and glycolysis - in a 24-well microplate, in real-time.

Service Area 2: Radiology; MRI and NMR and associated services


CENTER MEMBERS ARE REMINDED TO ACKNOWLEDGE THE UCSF NORC GRANT CONTRIBUTION IN THEIR PUBLICATION (P30DK098722)